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IMPaCT Trial

Individualised Molecular Pancreatic Cancer Therapy (IMPaCT) is a new clinical trial looking at individualising the treatment of patients with metastatic pancreatic cancer.

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Familial Cancer Cohort

If you would like to be involved in the project please click here to find out more.

 

Introduction

We have a range of snap frozen and formalin fixed paraffin embedded (FFPE) biospecimens, including tumour and matched normal tissues and blood components for some cases. The biospecimens are accompanied by a wealth of clinical and pathological information.

Annotated NSWPCN Tissue micro-arrays

Our collection includes one of the world's largest and most comprehensively annotated FFPE pancreatic tumour tissue cohort in micro-array format. This retrospectively acquired Australian surgical cohort spans over a decade, and is especially designed for rapid biomarker discovery studies. Pancreatic tumour types include pancreatic ductal adenocarcinomas, ampullary carcinomas, intraductal papillary mucinous neoplasms, pancreatic endocrine tumours and solid pseudo papillary tumours.

The above diagram shows two representative tissue micro-array cores viewed under light microscopy at medium to high magnification. Our arrays typically contain up to 96 cores per slide. On the left is an example of a moderately differentiated pancreatic ductal adenocarcinoma, while on the right is a poorly differentiated example.

Annotated ICGC Tissue micro-arrays

We are in the process of constructing FFPE pancreatic cancer tissue micro-arrays for prospectively collected tissue. Many of these have matched snap frozen and blood component material, accompanied by a rich clinicopathological dataset.

For further information about biospecimen availability and how you can use them for your research, please contact us at research@pancreaticcancer.net.au.